Tuesday Aug 12, 2025

The Strategic Trade Offs Behind Inference Time Compute Decisions

In this episode of Inference Time Tactics, Rob and Cooper dig into the strategic trade-offs driving a major shift in AI: why some enterprises start with closed models like OpenAI or Anthropic, then move to open-source stacks. The team breaks down the challenges of switching and how inference-time compute is becoming a competitive differentiator. They also unpack why pricing is shifting, how governance will evolve for this new layer, and what Rob learned from reviewing 250 research papers on reasoning algorithms.

 

We talked about: 

 

  • Insights from reviewing 250 research papers on reasoning algorithms. 

  • Why enterprises start with closed models like OpenAI or Anthropic before moving to open-source stacks. 

  • Challenges of switching stacks, including model fragmentation, capability gaps, and hardware choices. 

  • Cost-performance trade-offs when choosing inference architectures. 

  • How inference-time configuration can become a competitive differentiator. 

  • The role of pricing shifts and vendor lock-in in AI adoption. 

  • Emerging governance considerations for inference workflows. 

  • The growing variety and complexity of inference-time techniques.. 

  • Benchmarking challenges for multi-step and reasoning tasks. 

  • Why the lack of best practices makes inference optimization harder to operationalize. 

 
 

Connect with Neurometric:
Website: https://www.neurometric.ai/  

Substack: https://neurometric.substack.com/  

X: https://x.com/neurometric/  

Bluesky: https://bsky.app/profile/neurometric.bsky.social  

 

Hosts: 

Rob May 

https://x.com/robmay  

https://www.linkedin.com/in/robmay 

 

Calvin Cooper 

https://x.com/cooper_nyc_  

https://www.linkedin.com/in/coopernyc Comment end  

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